90% Identity; 50% Identity; Cross-references i … To achieve this feat, the research team took advantage of new chromatin-related sequencing technologies as well as detailed microscopic examination of chromosomes with fluorescent markers. ,2010) meaning that findings from Xenopus provide insights into many human conditions and diseases. Applications for the maternal host transfer technique combined with genome editing; Gene targeting and homology-directed repair; Circumventing lethal phenotypes; Xenopus genetics and husbandry issues arising in the creation of mutant lines; Both laevis and tropicalis will be used As pets. 90% Identity; 50% Identity; Cross-references i … reference database for MS/MS proteomics data, and/or RNA-seq data. Session et al. This page was last modified on 14 October 2014, at 09:06. The complete sequence of the 17,553-nucleotide Xenopus laevis mitochondrial genome has been determined. Data users may use data to analyze their own data, i.e. I converted original scaffold name to prevent confusion in comparison between different versions of the draft genome, because 'Scaffold102974' at XenBase/JGI 6.1 genome is different to 'Scaffold102974' at XenBase/JGI 7.2 genome. Studying genes involved in organogenesis is often difficult because many of these genes are also essential for early development. The GeneChip™ Xenopus laevis Genome 2.0 Array can be used to study the whole genome of Xenopus laevis on a single array. They display remarkable structural similarity with the human genome (Hellsten et al. Data users may freely download and analyze data. The earliest event in Xenopus development is the dorsal accumu-lation of nuclear β-catenin under the influence of cytoplasmic de-terminants displaced by fertilization. Genome Duplication Natural And Artificial Polyploidy (2n, 3n, 4n, 5n, 8n, 12n) The Xenopus genus includes various tetra-, octo- and dodecaploid species (Table 4) that were generated times over a period ranging from 80 to 10 millions years ago by interspecies hybridization through allopolyploidization (Evans et … Ancient whole genome duplications have been implicated in the vertebrate and teleost radiations, and in the emergence of diverse angiosperm lineages, but the evolutionary response to such a perturbation is still poorly understood. Xenopus laevis laevis has a yellowish to darker, spotted to marbled dorsal coloring. Egg production can be stimulated by injection of chorionic gonadotropin. They display remarkable structural similarity with the human genome (Hellsten et al. See Xenopus_Genome_Project_Consortium page for the members & contributors of the project. Xenopus laevis is an essential model organism in several areas of biology (see Harland & Grainger, TIG (2011) for review). Experimental organisms such as frogs (X. laevis and X. tropicalis), nematode worms (C. elegans), fruit flies (Drosphilia spp. Xenopus laevis (v9.1 genome assembly) L sub-genome, and (iii) XLA.S: X. laevis S sub-genome. The comparison with mammalian and bird genomes also provides an opportunity to examine the dynamics of tetrapod chromosomal evolution. This page has been accessed 550,953 times. The current version is named 'JGI 7.1' at XenBase, and 'JGIv7b' at UTA web repository('daudin'). In addition to the key attributes of these embryos for in vivo imaging, cell-free extracts from Xenopus provide among the most powerful in vitro systems for studies of cell and molecular biology. We searched the Xenopus tropicalis genome database (assembly version 1.0; Joint Genome Institute, Walnut Creek, CA; release date, December 10, 2003) using the TBLASTN protocol with amino acid sequences of the prohormones of goldfish urotensin I (GenBank accession no. in X. laevis is active, or whether both contribute to different elements of gene expression. They may use data in publications focused around individual genes. The allotetraploid frog, Xenopus laevis , is commonly used to study developmental processes, but because of the presence of two homeologs for many genes, it has been difficult to use as a genetic model. About the XGC. The frog Xenopus laevis has been an important model of vertebrate cell biology and development for many decades. The publication and presentation of global analysis of data with these sequences are not allowed until 'data owner' published the paper. ), zebrafish (Danio rerio) , chicken (Gallus Gallus) and mice (Mus musculus) are used to discover the molecular mechanisms fundamental to life, thereby providing a shortcut to understanding human biology. Texas Institute for Drug and Diagnostic Development, University of Texas Genome Sequencing and Analysis facility, http://daudin.icmb.utexas.edu/XENLA_JGIv72/, http://daudin.icmb.utexas.edu/XENTR_JGIv80/, http://gbrowse.xenbase.org/fgb2/gbrowse/xl7_1/, http://gbrowse.xenbase.org/fgb2/gbrowse/xt8_0/, http://daudin.icmb.utexas.edu/Oktoberfest/, http://hubble.icmb.utexas.edu/index.php?title=Xenopus_Genome_Project&oldid=1843, Attribution-Noncommercial-No Derivative Works 3.0 Unported. Advantages of Xenopus as a Model Organism Here, we first report on the generation of Xenopus laevis mutants with targeted single-base pair substitutions using this RNA-guided programmable deaminase. This subspecies has a fifth toe that is much longer than the tibia. GeneID i: 398006: KEGG i: xla:398006 Similar proteins i. Session et al. The African clawed frog Xenopus laevis experienced a relatively recent tetraploidization ~40 million years ago. The Xenopus Gene Collection (XGC) is an NIH initiative that supports the production of cDNA libraries, clones and 5'/3' sequences to provide a set of full-length (open reading frame) sequences and cDNA clones of expressed genes for Xenopus laevis and Xenopus tropicalis.All resources generated by the XGC are publicly accessible to the biomedical … Xenopus laevis have been kept as pets and research subjects since as early as the 1950s. Here, we first report on the generation of Xenopus laevis mutants with targeted single-base pair substitutions using this RNA-guided programmable deaminase. Genomes were aligned using Synteny Mapping and Analysis Program (SyMAP) v 4.2 [ … The array is comprised of more than 32,400 probe sets representing more than 29,900 X. laevis transcripts, and was designed in close collaboration with the Xenopus research community as part of the GeneChip Consortia Program. Initially, at the beginning of the 2000s, the tetraploid genome was thought to bring about problems that would not be observed if the diploid Xenopus tropicalis was chosen for sequencing. The genomes of both X. laevis and X. tropicalis have been sequenced. In particular, seamlessly combining data from two species, Xenopus laevis —a tetraploid, and Xenopus tropicalis —a diploid ( 2), in an integrated environment is complex. Female X. laevis laevis are larger than males and average 110 mm in length (Kobel et al., 1996). X. 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